Publications

- Mathiyazhagan R, Gupta PK, Kolkundkar U, Singh G, Balasubramanian S, SundarRaj S, Chullikana A & Anish S Majumdar., Preclinical safety and toxicity evaluation of a pooled, allogeneic human bone marrow-derived mesenchymal stromal cell product – Stempeucel. Ind J Med Res 144, December 2016, pp 852-864

- Ashwini P Aithal, Laxminarayana Kurady Bairy and Raviraja N Seetharam. Safety Assessment of Human Bone Marrow Derived Mesenchymal Stromal Cells Transplantation in Wistar Rats. Journal of Clinical and Diagnostic Research. 2017: 11 (9), FF01-FF03.

- Fakharuzi NA, Ahmad Zuhairi Abd Rahman, Singh G, Nurul Ain Nasim Mohd Yusof, Fakiruddin KS, Nian LM, Puteri J Noor M Baharuddin, Hamdan S, Majumdar AS, Zakaria Z “Non-Invasive In Vivo Tracking, Biodistribution And Fate Of Human Mesenchymal Stromal Cells (MSCs) In Rat Model” Regenerative Research 3(2) 2014 128-130

- Mamidi MK, Singh G, Husin JM, Nathan KG, Sasidharan G, Zakaria Z, Bhonde RR, Majumdar AS, (2012); Impact of passing mesenchymal stem cells through smaller bore size needles for subsequent use in patients for clinical or cosmetic indications J Transl Med. 2012; 10: 229.

- Pal R, Hanwate M, Totey SM. (2008) Effect of holding time, temperature and different parenteral solutions on viability and functionality of adult bone marrow-derived mesenchymal stem cells before transplantation. J Tissue Eng Regen Med, 2(7):436-44.

- Ashwini P. Aithal, Laxminarayana K. Bairy, Raviraja N. Seetharam. Safety and therapeutic potential of human bone marrow-derived mesenchymal stromal cells in regenerative medicine. Stem Cell Investig. 2021 May 11. 8:10. doi: 10.21037/sci-2020-036.

- Thej C, Ramadasse. B, Walvekar. A, Majumdar AS And Balasubramanian S Development of a surrogate potency assay to determine the angiogenic activity of Stempeucel®, a pooled, ex-vivo expanded, allogeneic human bone marrow mesenchymal stromal cell product. Stem Cell Research & Therapy (2017) 8:47

- Gupta PK, Dutta S, Krishna M, Sarkar U, Jeyaseelan L, Seetharam NS, Balasubramanian S, Chullikana A, Raju R, Viswanathan P, Thej C, Desai S, Dhar A, Murugesan R, Parakh R, Prasanth KV, Mathiyazhagan R, MajumdarAS (2016) “Administration of Adult Human Bone Marrow Derived, Cultured, Pooled, Allogeneic Mesenchymal Stromal Cells in Critical Limb Ischemia Due to Buerger’s Disease: Phase II Study Report Suggests Clinical Efficacy” Stem Cells Translational Medicine 2016;5:1–11.

- Pawan KG et al (2013)., Double Blind Randomized Placebo Controlled Phase I/II study assessing the safety and efficacy of Allogeneic Bone Marrow Derived Mesenchymal Stem Cell in Critical Limb Ischemia. J Transl Med. 2013 Jun 10;11:143. doi: 10.1186/1479-5876-11-143.

- Das AK, Basri A, Dhillon SS, Vijanari A, Anoop CH, Gupta PK: Intra arterial Allogeneic mesenchymal stem cells for critical limb ischemia are safe and efficacious: Report of a Phase I study. J Transl Med. 2013; 11: 143.

- Mamidi MK, Pal R, Dey S, Basri Johan Jeet Bin Abdullah, Zakaria Z, Rao MS & Das AK (2012). Cell therapy in critical limb ischemia: current developments and future progress. Cytotherapy Volume 14, Issue 8, September 2012, Pages 902–916

- Das A.K. (2009) Stem cell therapy for critical limb ischemia – a review: Indian J Surg. 2009 Aug;71(4):177-81. doi: 10.1007/s12262-009-0059-7. Epub 2009 Sep 2.

- Pawan Kumar Gupta, Santanu Dutta, Sanjay Kala, Muralikrishna Nekkanti, Sanjay C. Desai, Subhendu S. Mahapatra, Anita Dhar, Radhakrishnan Raju, Rajkumar M, Arunanshu Behera, Shivashankar P., N.S. Raviraja, Pachaiyappan Viswanathan, Mithun Chandrashekar, Charan Thej, Prasanth K.V., Jijy Abraham, Hema Boggarapu, K. Udaykumar. Phase IV PMS Study shows Continued Efficacy and Safety of stempeucel® in Patients with Critical Limb Ischemia due to Buerger’s Disease. Stem Cells Translational Medicine. STEM CELLS Transl Med. 2021;1-12. doi:10.1002/sctm.21-0197.

- Pawan Kumar Gupta, P. Shivashankar, M. Rajkumar, Subhendu S. Mahapatra, Sanjay C. Desai, Anita Dhar, Vinay Krishna, N. S. Raviraja, Samatha Bhat, Pachaiyappan Viswanathan, Suresh Kannan, Jijy Abraham, Hema Boggarapu, M. S. Manjuprasad1 and K. Udaykumar. Label extension, single‑arm, phase III study shows efficacy and safety of stempeucel®in patients with critical limb ischemia due to atherosclerotic peripheral arterial disease. Stem Cell Research & Therapy.2023.

- Gupta PK, Chullikana A, Mathiyazhagan R, Shetty N, Pandey V, Agarwal V, Wagh SY, Prasanth KV, Damodaran D, Vishwanathan P, Thej C, Balasubramanian S, Majumdar AS. Efficacy and safety of adult human bone marrow-derived, cultured, pooled, allogeneic mesenchymal stromal cells (Stempeucel®): preclinical and clinical trial in osteoarthritis of the knee joint. Arthritis Research & Therapy 2017. DOI 10.1186/s13075-016-1195-7.

- Gupta PK, Das AK, Chullikana A, Majumdar AS (2012), Mesenchymal Stem Cells for Cartilage Repair in Osteoarthritis. Stem Cell Research & Therapy)- 3:25 (9 July 2012)

- Gupta PK, Thej C, Mesenchymal stromal cells for the treatment of osteoarthritis of knee joint: context and perspective. Ann Transl Med, 2019. doi: 10.21037/atm.2019.07.54

- Vivek P, Sandesh M, Gupta PK :The promising role of autologous and allogeneic mesenchymal stromal cells in managing knee osteoarthritis. What is beyond Mesenchymal stromal cells?.Journal of Clinical Orthopaedics and Trauma.2022, doi.org/10.1016/j.jcot.2022.101804.

- Pawan Kumar Gupta, Sunil Maheshwari, Joe Joseph Cherian, Vijay Goni, Arun Kumar Sharma, Sujith Kumar Tripathy, KeerthiTalari, Vivek Pandey, Parag KantilalSancheti, Saurabh Singh Nikhil N. Verma and Uday Kumar.Efficacy and Safety of Stempeucel in Osteoarthritis of the Knee: A Phase 3 Randomized, Double-Blind, Multicenter, Placebo-Controlled Study. The American Journal of Sports Medicine, 2023. DOI: 10.1177/03635465231180323.

- Rengasamy.M; Singh.G; Fakharuzi.N.A; Siddikuzzaman; Balasubramanian.S; Swamynathan.P; Thej.C; Sasidharan. G; Gupta P.K; Das AK; Rahman AZA; Fakiruddin KS; Nian LM; Zakaria Z; Majumdar AS “Transplantation of human bone marrow mesenchymal stromal cells reduces liver fibrosis more effectively than Wharton's Jelly cells” Stem Cell Research & Therapy, 2017 ,SCRT-D-16-00502R1

- Ashwini P. Aithal , Laxminarayana K. Bairy , Raviraja N. Seetharam , Naveen Kumar Therapeutic Potential of Human Bone Marrow Derived Mesenchymal Stromal Cells in Combination with Silymarin against Carbon Tetrachloride Induced Liver Cirrhosis in Wistar Rats. JKIMSU, Vol. 6, No. 4, October-December 2017

- Aithal AP, Bairy LK and Seetharam RN“Safety Assessment of Human Bone Marrow-derived Mesenchymal Stromal Cells Transplantation in Wistar Rats”. Journal of Clinical and Diagnostic Research. 2017 Sep, Vol-11(9): FF01-FF03.

- Ashwini P. Aithal, Laxminarayana K. Bairy, Raviraja N. Seetharam, Naveen Kumar. Haemostatic potential of Human Bone Marrow derived Mesenchymal stromal cells in Wistar rats with carbon tetrachloride induced liver cirrhosis. Stem Cell Investigation, 2018,5:21

- Ashwini P. Aithal, Laxminarayana K. Bairy, Raviraja N. Seetharam, Mohandas KG. Rao. Human bone marrow‐derived mesenchymal stromal cells in combination with silymarin regulate hepatocyte growth factor expression and genotoxicity in carbon tetrachloride induced hepatotoxicity in Wistar Rats. J Cell Biochem. 2019;120:13026-13036.

- Pawan Kumar Gupta, Anoop Chullikana, Raviraja NS, Udaykumar K, Shivashankar P, Pachaiyappan Viswanathan, Mithun Chandrashekar, Charan Thej, Prasanth KV, Jijy Abraham and Anish Sen Majumdar. Phase II Dose Escalation Study of Intraarterial (Hepatic) Adult Human Bone Marrow Derived, Cultured, Pooled, Allogeneic Mesenchymal Stromal Cells (Stempeucel®) in Patients with Alcoholic Liver Cirrhosis. J Regenerative Medicine. 2021. doi: 10.31487/j.RGM.2021.01.02

- Ashwini P. Aithal, Laxminarayana K. Bairy, Raviraja N.,Seetharam, Naveen Kumar. Hepatoprotective effect of bone marrow‑derived mesenchymal stromal cells in CCl4‑induced liver cirrhosis. 3 Biotech. 2021 January 3. 11:107. doi.org/10.1007/s13205-021-02640-y.

- Chullikana A, MajumdarAS , Gottipamula S , Krishnamurthy S, Kumar AS, Prakash VS & Gupta PK “Randomized, double-blind, phase I/II study of intravenous allogeneic mesenchymal stromal cells in acute myocardial infarction” Cytotherapy, 2014; 0: 1-12 ( Dec 2014)

- Pal R, Gopinath C, Rao NM, Banerjee P, Krishnamoorthy V, Venkataramana NK & Totey.S (Oct 2010). Functional recovery after transplantation of bone marrow-derived human mesenchymal stromal cells in a rat model of spinal cord injury. Cytotherapy, 12(6), 792-806.

- Gopurappilly R, Pal R, Mamidi MK, Dey S, Bhonde R, Das AK. (2011)., Stem Cells in Stroke Repair: Current Success & Future Prospects. CNS Neurol Disord Drug Targets. 10: 741-756

- Das AK, Gopurappilly R, Parhar IS. (2011) Current status and prospective applications of stem cell-based therapy for spinal cord injury: A challenge for contemporary neurobiology: Curr. Stem Cell Res Ther. 6(2): 93-104.

- Pal R, Venkataramana NK, Bansal A, Balaraju S, Jan M, Chandra R, Dixit A, Rauthan A, Murgod U, Totey S. (2009) Ex vivo-expanded autologous bone marrow-derived mesenchymal stromal cells in human spinal cord injury/paraplegia: a pilot clinical study. Cytotherapy, 11(7): 897-911.

- Balasubramanian S, Thej C, Venugopal P, Priya N, Zakaria Z, SundarRaj S, Majumdar AS. Higher propensity of Wharton's jelly derived mesenchymal stromal cells towards neuronal lineage in comparison to those derived from adipose and bone marrow. Cell Biol Int. 2013 Jan 31. doi: 10.1002/cbin.10056. [Epub ahead of print]

- Dutta S, Singh G, Sreejith S, Mamidi MK, Husin JM, Datta I, Pal R, Das AK. Cell therapy: the final frontier for treatment of neurological diseases. CNS Neurosci Ther. 2013 Jan;19(1):5-11. doi: 10.1111/cns.12027.

- Dighe PA, Viswanathan P, Mruthunjaya AK, Seetharam RN. 2013. Effect of bFGF on HLA-DR expression of human Bone Marrow derived Mesenchymal Stem Cells. Journal of Stem cells, Volume 8 Issue 1.

- Gottipamula S, Muttigi MS, Chaansa S, Ashwin KM, Priya N, Kolkundkar U, SundarRaj S, Majumdar AS, Seetharam RN. Large-scale expansion of pre-isolated bone marrow mesenchymal stromal cells in serum-free conditions. J Tissue Eng Regen Med. 2013 Mar 12. doi: 10.1002/term.1713. [Epub ahead of print] PubMed PMID: 23495227.

- Mamidi MK, Nathan KG, Singh G, Thrichelvam ST, My NA, Fakharuzi NA, Zakaria Z, Bhonde R, Das AK, Majumdar AS. (2012) Comparative cellular and molecular analyses of pooled bone marrow multipotent mesenchymal stromal cells during continues passaging and after successive cryopreservation. J Cell Biochem. 2012 Oct;113(10):3153-64. doi: 10.1002/jcb.24193.

- Gottipamula S, Sharma A, Krishnamurthy S, Majumdar AS, Seetharam RN. Human platelet lysate is an alternative to fetal bovine serum for large-scale expansion of bone marrow-derived mesenchymal stromal cells. Biotechnol Lett. 2012 Jul; 34(7):1367-74. doi: 10.1007/s10529-012-0893-8. Epub 2012 Apr 4. PubMed PMID: 22476583.

- Balasubramanian S, Venugopal P, Sundarraj S, Zakaria Z, Majumdar AS, Ta M.., (2011) Comparison of Chemokine and Receptor Gene Expression between Wharton’s Jelly and Bone Marrow Derived Mesenchymal Stem Cells. Cytotherapy 11/2011; 14(1):26-33

- Das AK. (2011) Randomised Clinical trials in Surgery: a look at the ethical and practical issues Indian J of Surgery, & 3: 245-250 (DOI 10.1007/s12262-011-0307-5).

- Mamidi MK, Pal R, Govindasamy V, Zakaria Z, Bhonde R. (2011) Treat the graft to improve the regenerative ability of the host. Med Hypotheses, April; 776(4):599-601.

- Totey MS, Totey S, Pal R, Pal R. (2009) Adult Stem Cells: A Clinical Update. J Stem Cells. 2009;4(2):105-21.

- Pal R, Hanwate M, Jan M, Totey S. (2009) Phenotypic and functional comparison of optimum culture conditions for upscaling of bone marrow-derived mesenchymal stem cells. J Tissue Eng Regen Med. 2009 Mar;3(3):163-74. doi: 10.1002/term.143.

- Prasanna SJ, Gopalakrishnan D, Shankar SR, Vasandan AB. (2010) Pro-Inflammatory Cytokines, IFNγ and TNFα, Influence Immune Properties of Human Bone Marrow and Wharton Jelly Mesenchymal Stem Cells Differentially. PLoS One. 2010 Feb 2;5(2):e9016. doi: 10.1371/journal.pone.0009016.

- Neelam K Venkataramana, V Satishkumar K, Sudheer Balaraju, C.R.Radhika, Abhilash Bansal, Ashish Dixit, Deepthi K.R., Madhulita Das, Majahar Jan, Pawan Kumar Gupta, Satish Totey. (2010) Open labeled study of unilateral autologous bone marrow derived mesenchymal stem cells transplantation in Parkinson’s disease. Translational Research, 155(2)62-70.

- Majumdar AS et al (2012)., A leading Indian Stem cell company Developing cellular therapeutics for global consumers. Telegraft Vol. 19, No. 4 july 2012

- Gottipamula S, Ashwin KM, Muttigi MS, Kannan S, Kolkundkar U, Seetharam RN. Isolation, expansion and characterization of bone marrow derived stem cells in serum free conditions. Journal of Cell and Tissue Research. 2013. (DOI 10.1007/s00441-013-1783-7)

- Gottipamula S, Muttigi MS, Kolkundkar U, Seetharam RN. Serum free media for the production of human mesenchymal stem cells: A Review. Journal of Cell proliferation. 2013 Oct 04 doi: 10.1111/cpr.12063

- Kolkundkar U, Gottipamula S and Majumdar AS “Cell Therapy Manufacturing and Quality Control: Current Process and Regulatory Challenges” Review article J Stem Cell Res Ther 2014, 4:9

- Sanjay Gottipamula*, Samatha Bhat*, Udaykumar, Raviraja N Seetharam. Mesenchymal Stromal Cells: Basics, Classification and Clinical Applications. Journal of Stem Cells. 2018;13:01 (*equal contribution)

- Shoma Suresh K, Bhat S, Guru BR, Muttigi MS, Seetharam RN: A nanocomposite hydrogel delivery system for mesenchymal stromal cell secretome. Stem Cell Res Ther 2020, 11:205.

- Samatha Bhat, Geraldine Giap Ying Chiew, Jia Xing Ng, Xiangliang Lin, Raviraja N Seetharam. Optimization of Culture Conditions for Human Bone Marrow-Derived Mesenchymal Stromal Cell Expansion in Macrocarrier-Based Tide Motion System. Journal of Tissue Engineering and Regenerative Medicine. (Submitted)

- Samatha Bhat, Muthukumar Amirthalingam, Satish Pai B, Meghana B V, Pawan Kumar Gupta, Raviraja N Seetharam. Novel bioactive formulation derived from the conditioned medium of mesenchymal stromal cells reduces under-eye dark circles in human volunteers. Journal of clinical, cosmetic and investigational dermatology. (Under submission)

- Samatha Bhat, Pachaiyappan Viswanathan, Raviraja N Seetharam. Expansion and Characterization of Bone Marrow Derived Human Mesenchymal Stromal Cells in Serum-Free Conditions. Scientific Reports. (2021) 11:3403

- Charan Thej et al. Comparison of several key properties of bone marrow-derived mesenchymal stromal cells obtained from six individual donor-derived mesenchymal stromal cells and multiple donor-derived mesenchymal stromal cell pool (s) that are critical for therapeutic use. (Under submission)

- Charan Thej*, Sudha Balasubramanian*, Mathiyazhagan Rengasamy, Ankita Walvekar, Priyanka Swamynathan, Swathi SundarRaj, Pradnya Sahani, Siddikuzzaman, Udaykumar Kolkundkar, Raviraja N Seetharam, Pawan Kumar Gupta, Anish Sen Majumdar. Human bone marrow-derived, pooled, allogeneic mesenchymal stromal cells manufactured from multiple donors at different time intervals show comparable biological functions, both in vitro and in vivo to repair limb ischemia. Stem Cells Translational Medicine. (Under submission).

- Tomohiro Yoneda, Byung H. Choi, Pawan K. Gupta, Chih-Yuan Ho, Yat P. Tsui, Ling-Mei Wang, Yukari Fujiwara, Hiroshi Karasawa, Yuu Moriya, Kiyoko Bando, Yoshiteru Kamiyama, Masayuki Kanki, Kou Omura, Takeshi Watanabe, Yohan Bae, Feng-Cheng Chou1, Dong-sik Ham, Joo Y. Lee, Guangyang Liu, Yongjun Liu, James Ooi, Yoshie Tsurumaki. Non-clinical assessment of cell therapy products: the perspective from five Asian countries/regions based on regulatory guidelines and the underpinning rationales. Cytotherapy. 2021 Apr 20. doi : doi.org/10.1016/j.jcyt.2021.04.007.

- Sufyan Ibrahim, Himanshu Y. N., Raviraja N. Seetharam, Kavitha Saravu. A comparison of strengths and weaknesses of mesenchymal stem cell based versus natural killer cell based therapeutics for COVID-19. Indian Journal of Hospital Pharmacy. 2021

- T. Yoneda, T. Tanaka, K. Bando, B.H. Choi, R Chang, Y. Fujiwara, P.K. Gupta, D.S. Ham, H. Karasawa, S. Kuwae, S.M. Lee, Y. Moriya, K. Takakura, Y. Tsurumaki, T. Watanabe, K. Yoshimura, M. Nomura. Nonclinical and quality assessment of cell therapy products: Report on the 4th Asia Partnership Conference of Regenerative Medicine, April 15,2021.Cytotherapy. 2022. https://doi.org/10.1016/j.jcyt.2022.01.005.

- Toshimitsu Tanaka, Keiji Yoshimura, Ryan Chang , Bryan Choi, Ying Gai , Pawan Kumar Gupta, UdaykumarKolkundkar, Shing-Mou Lee, Sunray Lee, Wenbin Liao, Xiang Zhao, Koji Takakura. Comparison of guidelines for biological ancillary materials used for the manufacture of gene and cellular therapy products in Asia.Cytotherapy. 2022. DOI: 10.1016/j.jcyt.2022.09.005.

- S. Subramanian Shanmugam,  G. Krishna, P.K. Gupta, U. Kumar. Novel pooling technology overcomes the heterogeneity among the individual donor derived bone marrow Mesenchymal stromal cell. Cytotherapy, Volume 25, Issue 6, E1 - E2

- Amirthalingam. M, Seetharam R N. Stem Cell Derived Cosmetic Products: An overview- Review article Manipal Journal of Medical Sciences | December 2016 | Volume 1 | Issue 2

- “Evaluation of the secretome profile and functional characteristics of human Bone Marrow Mesenchymal Stromal Cells (BMMSC) derived conditioned medium suggest potential for skin rejuvenation” Journal of Cosmetics, Dermatological Sciences and Applications, 2017, 7, 99-117

- Sachdev M, Chullikana A,. Seetharam R N, Shilpakar R, Sapna R, Velugotla.K, Ritambhara,. Majumdar AS, Gupta PK “A Single Arm, Monocentric, Prospective, Open Label Study to Evaluate Anti-Ageing Efficacy of Human Growth Factors and Cytokines Containing Cosmetic Skin Serum in Indian Female Population” Journal of Cosmetics, Dermatological Sciences and Applications, 2017, 7, 118-132.

- Muthukumar Amirthalingam*, Samatha Bhat*, Pratiksha A Dighe and Raviraja N Seetharam. Human Mesenchymal Stromal Cells-Derived Conditioned Medium Based Formulation for Advanced Skin Care: in vitro and in vivo Evaluation. J Stem Cell Res Dev Ther. 2019; 4: 012. (*equal contribution) .

- SundarRaj S, Deshmukh A, Priya N, Krishnan VS, Cherat M, and Majumdar AS, “Development of a System and Method for Automated Isolation of Stromal Vascular Fraction from Adipose Tissue Lipoaspirate,” Stem Cells International, vol. 2015, Article ID 109353, 11 pages, 2015. doi:10.1155/2015/109353.

- Priya N, Sarcar S, Majumdar AS, SundarRaj S.,(2012) Explant culture: a simple, reproducible, efficient and economic technique for isolation of mesenchymal stromal cells from human adipose tissue and lipoaspirated Journal of Tissue Engineering and Regenerative Medicine.2012 DOI: 10.1002/term.1569

- SundarRaj S, Priya N, Deshmukh A, Cherat M and Majumdar AS(July 2013)., Development of an Automated Device for Point-Of-Care Isolation of Stromal Vascular Fraction Cells from Adipose Tissue Lipoaspirate. IPRAS Journal, July 2013, Issue 13, 43-44.

- Sivasubramaniyan K, Atluri RR, Sarda K, Arvind M, Balaji V, Deb KD. (2008) Endotoxin-induced silencing of mesoderm induction and functional differentiation: role of HMGB1 in pluripotency and infection. Regen Med, 3(1): 23-31.

- Deb KD, Sarda K. (2008) Human embryonic stem cells: preclinical perspectives. J Transl Med, 29: 6-7.

- Deb KD, Jayaprakash AD, Sharma V, Totey S. (2008) Embryonic stem cells: from markers to market. Rejuvenation Res, 11(1): 19-37

- Saxena S, Hanwate M, Deb K, Sharma V, Totey S. (2008) FGF2 secreting human fibroblast feeder cells: a novel culture system for human embryonic stem cells. Mol Reprod Dev, 75(10): 1523-32.

- Pal R. (2009) Embryonic stem (ES) cell-derived cardiomyocytes: a good candidate for cell therapy applications. Cell Biol Int, 33(3): 325-36.

- Deb KD. (2009) A sweet potion to put embryonic stem cells to sleep. Scientific World Journal, 9: 236-49.

- Sivasubramaiyan K, Totey S, Bhat V, Totey SM, Deb K. (2009) Y-27632 enhances differentiation of blastocyst like cystic human embryoid bodies to endocrinologically active trophoblast cells on a biomimetic platform. J Biomed Sci, 16(1): 88.

- Pal R, Totey S, Mamidi MK, Bhat VS, Totey S. (2009) Propensity of human embryonic stem cell lines during early stage of lineage specification controls their terminal differentiation into mature cell types. Exp Biol Med (Maywood), 234(10): 1230-43

- Sivasubramaniyan K, Pal R, Totey S, Bhat VS, Totey S. (2010) Rho Kinase Inhibitor Y27632 Alters the Balance Between Pluripotency and Early Differentiation Events in Human Embryonic Stem Cells. Curr Stem Cell Res Ther, 5(1):2-12(11).

- Mamidi MK, Pal R, Bhonde R, Zakaria Z, Totey S 2010. Application of Multiplex PCR for Characterization of Human Embryonic Stem Cells (hESCs) and Its Differentiated Progenies. J Biomol Screen, 15(6): 630-643.

- Nekanti U., Mohanty L., Venugopal P., Balasubramanian S., Totey S. and Ta M. 2010. Optimization and Scale up of Wharton's Jelly-derived Mesenchymal Stem Cells for Clinical Applications. Stem Cell Res. Nov;5(3):244-54.

- Venugopal P, Balasubramanian S, Majumdar AS, Ta.M (2011) "Isolation, Characterization and Gene Expression Analysis of Wharton's Jelly-derived Mesenchymal Stem Cells under Xenofree Culture Conditions" Stem Cells and Cloning: Advances and Applications, 4: 39–50.

- Mamidi MK, Pal R, Binti Mori NA, Arumugam G, Thrichelvam ST, Noor PJ, Farouk Abdullah HM, Gupta PK, Das AK, Zakaria Z and Bhonde R. (2011) Co-culture of mesenchymal-like stromal cells derived from human foreskin permits long term propagation and differentiation of human embryonic stem cells. Journal of Cellular Biochemistry, May; 112(5): 1353-63

- Pal R, Mamidi MK, Das AK and Bhonde RR(2011)., Human embryonic stem cell proliferation and differentiation as parameters to evaluate developmental toxicity. Journal of Cellular Physiology Volume 226, Issue 6, June 2011, Pages: 1583–1595.

- Pal R, Mamidi MK, Das AK, Gupta PK, Bhonde R.., (2011), A Simple and economical route to generate functional hepatocyte-like cells from hESCs and their application in evaluating alcohol induced liver damage: J Cell Biochem. 2012 Jan; 113 (1):19-30.

- Bankapur A, Krishnamurthy RS, Zachariah E, Santhosh C, Chougule B, et al. (2012) Micro-Raman Spectroscopy of Silver Nanoparticle Induced Stress on Optically-Trapped Stem Cells. PLoS ONE 7(4): e35075. doi:10.1371/journal.pone.0035075

- Pal R, Mamidi MK, Das AK, Bhonde R: Diverse effects of dimethyl sulfoxide (DMSO) on the differentiation potential of human embryonic stem cells Arch Toxicol. 2012 Apr;86(4):651-61. [PubMed - 22105179] [Impact factor 4.26].

- Pal R, Mamidi MK, Das AK, and Bhonde R. A comparative analysis of cardiomyocyte differentiation from human embryonic stem cells under 3-D and 2-D culture conditions. J Biosci Bioeng. 2012 Oct 5. doi:pii: S1389-1723(12)00361-1. 10.1016/j.jbiosc.2012.08.018. [Epub ahead of print]

- L Aishwarya, Dharmarajan Arun, Suresh Kannan. Stem Cells as a Potential Therapeutic Option for Treating Neurodegenerative Diseases. Current Stem Cell Research & Therapy. 2021; 1-16. doi:10.2174/1574888X16666210810105136

- Nekanti U, Rao VB, Bahirvani AG, Jan M, Totey S and Ta M. (2010) Long-term Expansion and Pluripotent Marker Array Analysis of Wharton’s Jelly-Derived Mesenchymal Stem Cells. Stem Cells Dev, 19(1): 117-130.

- Nekanti U., Dastidar S., Venugopal P., Totey S. and Ta M. (2010) Increased proliferation and analysis of differential gene expression in human Wharton’s Jelly-derived mesenchymal stromal cells under hypoxia. Int. J. Biol. Sci,. 6(5):499-512.

- Swamynathan P, Venugopal P, Kannan S, Thej C, Kolkundar UK, Bhagwat S, Ta M, Majumdar AS, Balasubramanian S. Are serum-free and xeno-free culture conditions ideal for large scale clinical grade expansion of Wharton's jelly derived mesenchymal stem cells? A comparative study. Stem Cell Res Ther. 2014 Jul 28;5(4):88. [Epub ahead of print] PubMed PMID: 25069491.

-Suresh Kannan, Pachaiyapan, UdayKumar, Pawan Kumar Gupta, Characteristics of Pooled Wharton’s jelly Mesenchymal stromal cells (WJ-MSCs) and their potential role in Rheumatoid arthritis treatment, Stem Cell Reviews and Reports, 2022. https://doi.org/10.1007/s12015-022-10344-w

- Das A and Pal R. (2010) Induced pluripotent stem cells (iPSCs): the emergence of a new champion in stem cell technology-driven biomedical applications. J Tissue Eng Regen Med, 4: 413–421. doi: 10.1002/term.258.

- Govindasamy V, Abdullah AN, Ronald VS, Musa S, Zeti Adura Che Ab. Aziz, Zain RB, Totey S,. Bhonde R R, Kasim NHA. (2010) Inherent differential propensity of dental pulp stem cells derived from human deciduous and permanent teeth. Journal of endodontics, 36(9); 1504-1515, DOI: 10.1016/j.joen.2010.05.006.

- Govindasamy V, Ronald VS, Totey S, Din SB, Wan Mahadzir Bin Wan Mustafa, Totey S, Zakaria Z, Bhonde RR. (2010) Micromanipulation of culture niche permits long term expansion of dental pulp stem cells - an economic and commercial angle," In Vitro Cell Dev Biol Anim. 46(9):764-73.

- Govindasamy V, Ronald VS, Abdullah AN, Ganesan Nathan KR, Ab Aziz ZA, Abdullah M, Musa S, Abu Kasim NH, Bhonde RR. (2011) Differentiation of Dental Pulp Stem Cells Into Islet Like Aggregates. J Dent Res. May; 90(5):646-52.

- Govindasamy V, Ronald VS, Abdullah AN, Ganesan Nathan KR, Aziz ZA, Abdullah M, Zain RB, Kasim NH, Musa S, Bhonde RR. ( 2011) Human platelet lysate permits scale-up of dental pulp stromal cells for clinical applications. Cytotherapy, 1–13.